WILD BEES AND THEIR NESTS HOST PAENIBACILLUS BACTERIA WITH FUNCTIONAL POTENTIAL OF AVAIL



Transcriptome analysis of Homo sapiens and Mus musculus reveals mechanisms of CD8+ T cell exhaustion caused by different factors.

T cell exhaustion is a state of T cell dysfunction during chronic infection and cancer.Antibody-targeting immune checkpoint inhibitors to reverse T cell exhaustion is a promising approach for cancer immunotherapy.However, molecular mechanisms of T cell exhaustion remain incompletely understood.Here, we performed a transcriptome analysis by integrat

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LINC01355 Contributes to Malignant Phenotype of Oral Squamous Cell Carcinoma and Cytotoxic T Cell Infiltration via Activating Notch Signaling Pathway

LINC01355 has been demonstrated to be dysregulated in several cancers.However, the exact molecular function of LINC01355 in the pathogenesis of OSCC remains unstudied.Here, we reported the effect of LINC01355 in OSCC and investigated the mechanisms.Firstly, we found that the results indicated LINC01355 was increased in OSCC cells.Knockdown of LINC0

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Historical rural architecture of North Portugal and Spanish Galicia: local vernacular forms and concept of adaptation, case study of Porreiras

Vernacular forms which can be found in North Portugal and Galicia (region of Western Spain) can be traced down up until times, when this geographical area was bound together through Celtic influences.Wood, stone, and clay, used for local constructions, appear in many forms which are until now well preserved around the area.The main objective of res

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